Quinolin-3yl-chalcones and Derivatives: Synthesis of pyrazoline derivatives from 3-acetyl-6-chloro-4-phenylquinoline

Description

The content of this book describes that the efficient synthesis of 6-chloro-2-methyl-4-phenylquinolin-3-yl)-3-aryl-prop-2-en-1-ones (Chalcones) from 6-chloro-2-methyl-4-phenylquinoline and their efficient conversion into pyrazoline derivatives. Since the quinoline, chalcone pharmacophore and pyrazoline moiety are having biological importance. If they have been associated together as a single molecule the respective individual biological activity may be pronounced with this idea the synthesis of some new quinoline derivatives have been proposed, synthesized and characterized using spectral and single crystal X-ray diffraction studies and presented,further they will be explored for their activities.